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SAM-dependent hydroxylase The first example of a SAM-dependent hydroxylase is RdmB, which catalyzes decarboxylative hydroxylation of 15-demethoxy--rhodomycin (125) to form the anthracycline precursor -rhodomycin (126)
These mechanistic actions have been consistently verified in various disease models, including atherosclerosis, intestinal ischemiareperfusion injury (IIRI), and pulmonary ischemiareperfusion injury (LIRI) [341,342,343]
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Conserver hors de la porte des enfants
