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All procedures were performed in strict adherence to the manufacturers instructions for the Siemens original reagents

Protein degradation by the UPS is executed through a complex three-step enzymatic cascade involving ubiquitin-activating enzymes (E1), ubiquitin-conjugating enzymes (E2) and ubiquitin ligases (E3)

298 The JAK/STAT signaling pathway The signal transducer and activator of transcription (STAT) signaling pathway is involved in the control of vital biological processes such as cell growth, differentiation and the immune response

doi: 10.1016/j.canlet.2022.215929, 82 LuoH.XiangY.QuX.LiuH.LiuC.LiG.et al

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