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Semaglutide is a GLP-1 receptor agonist that mimics the hormone, making you feel less hungry

Effect of vertical sleeve gastrectomy on alcohol consumption and preferences in dietary obese rats and mice: a plausible role for altered ghrelin signaling

Both medications belong to the incretin family, but have different mechanisms of action, dosing, FDA-approved uses, and side effect profiles

GLP-1 receptor agonists predominantly target non-MC4R-dependent neural pathways in mice 19 , and there is evidence from a small clinical study with liraglutide 20 that they may be effective in people with MC4R deficiency