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Their main job is to make the uterus contract rhythmically so it can shed its lining that squeezing sensation is exactly what you feel as a cramp

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However, most of this evidence comes from case reports and small observational cohorts, with a conspicuous lack of large-scale prospective trials

Additional testing may be considered for people with a family history of premature heart disease, metabolic risk, abnormal cholesterol results, known cardiovascular disease, or uncertainty after standard testing: ApoB, Lp(a), and hs-CRP may help reveal particle burden, inherited risk, and inflammation that are not fully captured by LDL cholesterol alone

Perhaps recklessly, Im going to suggest that a comparison might be drawn to medicinal cannabis