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Patients with a del15q genotype tend to have higher BMI (137, 176, 177) and HbA1c levels, despite similar values of glycemia, insulinemia, insulin resistance, body composition, metabolic profile, adipocyte size, resting energy expenditure, hyperphagia score, and levels of ghrelin compared to those with mUPD, suggesting a possible association between mUPD genotype and a more adverse metabolic profile, even when adjusted for BMI

Cardiovascular effects beyond cardiac hypertrophy are poorly characterized for IGF-1 DES specifically, though IGF-1 influences cardiovascular physiology through effects on vascular smooth muscle, endothelial function, blood pressure regulation, and cardiac contractility - chronic perturbation of these processes carries unknown risks

Sodium-glucose cotransporter-2 (SGLT2) inhibitors represent a revolutionary approach in the treatment of type 2 diabetes

Dedifferentiation and reprogramming: origins of cancer stem cells

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