FH1 - Hepatocytes Functional Enhancer. CAS# 2719-05-3 size:2 mg solid 4-dihydrophthalazin-1-yl)ethyl)benzamide

4-dihydrophthalazin-1-yl)ethyl)benzamide

is a cell permeable and selective novel active-site KDM4A/KDM4B inhibitor with IC50 ~6

2-hydroxyglutarate (2HG)

Shelf Life: ≥12 months if stored properly

Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster

FH1 - Hepatocytes Functional Enhancer. CAS# 2719-05-3 size:2 mg solid 4-dihydrophthalazin-1-yl)ethyl)benzamideFH1, CAS No. 2719 05 3, is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC derived hepatocytes toward a more mature phenotype in vitro. FH1 was identified by a high throughput, cell based screening using primary human hepatocytes. It was added to the basal medium with or without OSM on day 21 after the initiation of differentiation of iPSCs and acted over a period of 9