HEM6 Rabbit Polyclonal Antibody, 100ul Biochemical Reagents ADGRB1) contains at least one

ADGRB1) contains at least one 'functional' p53-binding site within an intron

As such it functions as a negative regulator of many signal transduction pathways

Pro-cathepsin H encoded by CTSH is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins

Interacts with the PDZ domain of SHANK1

inhibiting MAP3K3-mediated interleukin-8 production

HEM6 Rabbit Polyclonal Antibody, 100ul Biochemical Reagents ADGRB1) contains at least oneThe protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).