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Possible Side Effects Mild side effects of Vitamin B12 may include: ( 12 ) Mild pain, itching, or swelling at the injection site Temporary nausea or headache Mild diarrhea Hot flashes Vomiting These side effects do not affect all patients and are generally temporary and mild While rare, more serious side effects of Vitamin B12 injections can include ( 12 ): Irregular heartbeat Heart palpitations Hives or skin rash If you notice any severe reactions to a Vitamin B12 shot, contact a medical professional immediately

There does seem to be some confusion about harm and temporary effects as the B12 takes effect

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These shots deliver a concentrated dose of vitamin B12 directly into the bloodstream, bypassing the digestive system for maximum absorption