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Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 PAI-039 is a small-molecule inhibitor

Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 PAI-039 is a small-molecule inhibitor

Name: Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 PAI-039 is a small-molecule inhibitor
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Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 PAI-039 is a small-molecule inhibitorSu 11274, CAS No. 658084 23 2, is a selective Met tyrosine kinase inhibitor with IC50 of 10 nM. Su 11274 increases tumorigenicity and enriched for melanoma initiating cells by bioenergetic modulation. Su 11274 suppresses proliferation and motility of pancreatic cancer cells. Su 11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation. Su 11274 exhibits a selective inhibition pattern toward different receptor mutated

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Description

PAI-039 is a small-molecule inhibitor of PAI-1 activity

Upon administration

(1997) Nature

PKD3 IC50 = 0

and TEL-PDGFβR

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