TdT Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Most WFDC gene members are

Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric

Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes

This gene belongs to the hyaluronan and proteoglycan binding link protein gene family

DBX1 (Developing Brain Homeobox 1) is a Protein Coding gene

suggesting that it may participate in redox regulation of the enzyme

TdT Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Most WFDC gene members areDNTT is a member of the DNA polymerase type X family and encodes a template independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3' hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre B and pre T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non germ line elements (N regions)