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Nat Rev Gastroenterol Hepatol 14:110121 Sobczak M, Fabisiak A, Murawska N, Wesoowska E, Wierzbicka P, Wlazowski M, Wjcikowska M, Zatorski H, Zwoliska M, Fichna J (2014) Current overview of extrinsic and intrinsic factors in etiology and progression of inflammatory bowel diseases

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As expected, treatment with sitagliptin led to a significant reduction in plasma DPP-4 activity at 12 months, but the levels of soluble DPP-4 and inflammatory markers remained unchanged [25]

Novel gut microbiota modulator, which markedly increases akkermansia muciniphila occupancy, ameliorates experimental colitis in Rats