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p70 S6 kinase Alpha Polyclonal Antibody, 100ul[BT-AP06858] Diagnostic Probes & Oligos A HECT (homology to E6-AP

SKU: 82971105724

4.6
SEK123.75 SEK160.75

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p70 S6 kinase Alpha Polyclonal Antibody, 100ul[BT-AP06858] Diagnostic Probes & Oligos A HECT (homology to E6-APRPS6KB1 (ribosomal protein S6 kinase B1) encodes a member of the ribosomal S6 kinase family of serine threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of RPS6KB1 has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms

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Description

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

This protein shares 97%

An important paralog of POU3F1 is POU6F1

The protein is a member of the SLC38 sodium-coupled neutral amino acid transporter family of proteins

gamma and delta polypeptides are located in the same cluster on chromosome 11

p70 S6 kinase Alpha Polyclonal Antibody, 100ul[BT-AP06858] Diagnostic Probes & Oligos A HECT (homology to E6-APRPS6KB1 (ribosomal protein S6 kinase B1) encodes a member of the ribosomal S6 kinase family of serine threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of RPS6KB1 has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms

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